Successful resolution of refractory chronic cough induced by gastroesophageal reflux with treatment of baclofen
نویسندگان
چکیده
Gastroesophageal reflux induced cough is a common cause of chronic cough, and proton pump inhibitors are a standard therapy. However, the patients unresponsive to the standard therapy are difficult to treat and remain a challenge to doctors. Here, we summarized the experience of successful resolution of refractory chronic cough due to gastroesophageal reflux with baclofen in three patients. It is concluded that baclofen may be a viable option for gastroesophageal reflux induced cough unresponsive to proton pump inhibitor therapy.
منابع مشابه
There are still problems in establishing a diagnosis of gastroesophageal reflux-related chronic cough.
A recent study of 281 patients with extraesophageal syndromes of gastroesophageal refl ux disease, of whom 50% had a cough, estimated that 52% of the overall US national annual economic burden of extraesophageal syndromes was attributable to proton pump inhibitor therapy. 1 It is becoming increasingly important to identify patient populations likely to be responsive, avoiding unnecessary or ina...
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